How does travel, specifically immigration, affect the epidemiology of chronic disease? For Asian American/Pacific Islander (AAPI) immigrants, an unusually high rate of diabetes is puzzling, given the group’s relatively low rate of obesity and other typical causes of diabetes. The unique mix of AAPI patients in a free health clinic of Philadelphia’s Chinatown (half Chinese, half Malays) is the basis for this study of how immigration affects health and lifestyle.